Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL11209772 | 1.00 | LMNA (0.52) | LMNAMAPK1KEAP1NFE2L2ALOX5 | |
| Alanine SCHEMBL11204313 | 1.00 | LMNA (0.52) | LMNAMAPK1KEAP1NFE2L2ALOX5 | |
| D-Alanine SCHEMBL11207612 | 1.00 | LMNA (0.52) | LMNAMAPK1KEAP1NFE2L2ALOX5 | |
| D-Alanine SCHEMBL11496478 | 0.98 | LMNA (0.50) | LMNAMAPK1KEAP1NFE2L2ALOX5 | |
| SCHEMBL366066 | 0.90 | LMNA (0.62) | LMNAMAPK1KEAP1NFE2L2ALOX5 | |
| SCHEMBL245404 | 0.90 | LMNA (0.62) | LMNAMAPK1KEAP1NFE2L2ALOX5 | |
| SCHEMBL245405 | 0.90 | LMNA (0.62) | LMNAMAPK1KEAP1NFE2L2ALOX5 | |
| SCHEMBL11835765 | 0.84 | LMNA (0.56) | LMNAMAPK1KEAP1NFE2L2BLM | |
| Alanine SCHEMBL11206225 | 0.83 | LMNA (0.50) | LMNAMAPK1BLMNPSR1TSHR | |
| D-Alanine SCHEMBL11211250 | 0.83 | LMNA (0.50) | LMNAMAPK1BLMNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009722-B1 | OPTICALLY ACTIVE COMPLEX, ALANINE.RING-SUBSTITUTED MANDELIC ACID, AND THE METHOD FOR PRODUCING THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-03-02 | — | — | EP | claimed |
| EP-0009722-A1 | Optically active complex, alanine.Ring-substituted mandelic acid, and the method for producing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | claimed |