Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208607 | 0.75 | TUBB1 (0.41) | ALOX5PTGS1PTGS2SMN1; SMN2LMNA | |
| SCHEMBL11209825 | 0.74 | PARP1 (0.38) | ALOX5PARP1SMN1; SMN2LMNAPOLB | |
| SCHEMBL11210047 | 0.71 | PARP1 (0.41) | ALOX5PARP1POLBMAPTTDP1 | |
| SCHEMBL11291271 | 0.71 | NPC1 (0.51) | ALOX5PTGS1PTGS2PARP1GAA | |
| SCHEMBL11204477 | 0.71 | MAPT (0.43) | HSD17B10SMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL11291273 | 0.71 | NPC1 (0.51) | ALOX5PTGS1PTGS2PARP1GAA | |
| SCHEMBL11210833 | 0.69 | TAAR1 (0.55) | ALOX5PTGS1PTGS2SMN1; SMN2KDM4E | |
| SCHEMBL11209121 | 0.69 | LMNA (0.42) | LMNANPSR1TDP1ALDH1A1 | |
| SCHEMBL11790300 | 0.67 | ALOX5 (0.55) | ALOX5PTGS1PTGS2GAAHSD17B10 | |
| SCHEMBL11790340 | 0.67 | ALOX5 (0.55) | ALOX5PTGS1PTGS2GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034474-B1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Farmos-Yhtyma Oy (FI) | 1983-01-26 | — | — | EP | disclosed |
| US-4333947-A | HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES | FARMOS-YHTYMA OY (FI) | 1982-06-08 | — | — | US | disclosed |
| EP-0034474-A1 | Substituted imidazoles, their preparation and pharmaceutical compositions containing the same | Farmos-Yhtyma Oy (FI) | 1981-08-26 | — | — | EP | disclosed |