Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 4/20 | 0.37 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.37 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210833 | 0.77 | TAAR1 (0.55) | IP6K1IP6K3IP6K2POLBMAPT | |
| SCHEMBL11210835 | 0.77 | TAAR1 (0.55) | IP6K1IP6K3IP6K2POLBMAPT | |
| SCHEMBL11208575 | 0.75 | ALOX5 (0.45) | POLBMAPTTDP1ALOX5SMN1; SMN2 | |
| SCHEMBL10974637 | 0.75 | TUBB1 (0.61) | TUBB1POLBMAPTTDP1ALOX5 | |
| SCHEMBL10974635 | 0.75 | TUBB1 (0.61) | TUBB1POLBMAPTTDP1ALOX5 | |
| SCHEMBL11210047 | 0.72 | PARP1 (0.41) | POLBMAPTTDP1TAAR1ALOX5 | |
| SCHEMBL11289761 | 0.70 | NPC1 (0.45) | TUBB1POLBMAPTTDP1TAAR1 | |
| SCHEMBL11289759 | 0.70 | NPC1 (0.45) | TUBB1POLBMAPTTDP1TAAR1 | |
| SCHEMBL11209825 | 0.69 | PARP1 (0.38) | POLBMAPTTDP1TAAR1ALOX5 | |
| SCHEMBL11205980 | 0.67 | NPC1 (0.46) | POLBMAPTTDP1ALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034474-B1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Farmos-Yhtyma Oy (FI) | 1983-01-26 | — | — | EP | disclosed |
| US-4333947-A | HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES | FARMOS-YHTYMA OY (FI) | 1982-06-08 | — | — | US | disclosed |
| EP-0034474-A1 | Substituted imidazoles, their preparation and pharmaceutical compositions containing the same | Farmos-Yhtyma Oy (FI) | 1981-08-26 | — | — | EP | disclosed |