SCHEMBL11273083

SCHEMBL11273083

O=C(O)c1ccc(OC(=O)c2cccc(C(=O)Oc3ccc(C(=O)O)cc3)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.58
MAPT P10636 7/20 0.54
TDP1 Q9NUW8 3/20 0.54
KMT2A Q03164 8/20 0.53
MEN1 O00255 5/20 0.53
MAPK1 P28482 3/20 0.53
PKM P14618 2/20 0.53
KDM4E B2RXH2 2/20 0.53
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
MITF O75030 1/20 0.53
MCL1 Q07820 1/20 0.53
ATM Q13315 1/20 0.53
ALDH1A1 P00352 3/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
HSD17B10 Q99714 1/20 0.50
NSD2 O96028 1/20 0.49
CA1 P00915 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11040365 0.96 PARP10 (0.59) PARP10MAPTTDP1KMT2AMEN1
Terephthalic Acid SCHEMBL10678592 0.94 MAPT (0.57) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL8848151 0.94 LMNA (0.56) PARP10MAPTTDP1KMT2AMEN1
Terephthalic Acid SCHEMBL6660728 0.93 AKR1C3 (0.58) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL28207082 0.92 ACR (0.52) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL22065394 0.90 HSD17B10 (0.55) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL8205804 0.90 CA12 (0.61) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL995523 0.89 AKR1C3 (0.61) PARP10MAPTTDP1KMT2AMEN1
SCHEMBL622771 0.88 PARP10 (0.72) PARP10MAPTTDP1KMT2AMEN1
Isophthalic Acid SCHEMBL7913012 0.88 LMNA (0.59) PARP10MAPTTDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0052927-A2 Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-06-02 EP disclosed