Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203013 | 0.82 | ALDH1A1 (0.41) | CA1CA2ADAMTS4ALDH1A1EGFR | |
| SCHEMBL11204093 | 0.80 | CA2 (0.39) | CA1CA2ALDH1A1EGFRLMNA | |
| SCHEMBL11204902 | 0.75 | SMN1; SMN2 (0.39) | CA1CA2ALDH1A1LMNAHPGD | |
| SCHEMBL11204056 | 0.71 | KDM4E (0.34) | ADAMTS4ALDH1A1LMNAMMP2MMP9 | |
| SCHEMBL297076 | 0.71 | LTA4H (0.44) | ALDH1A1 | |
| SCHEMBL11209033 | 0.70 | MAOB (0.43) | LMNAMMP9HSD17B10 | |
| SCHEMBL11211500 | 0.70 | KMT2A (0.34) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL11205508 | 0.68 | BACE1 (0.35) | — | |
| SCHEMBL8864422 | 0.65 | ACHE (0.41) | CA1CA2ADAMTS4ALDH1A1EGFR | |
| SCHEMBL9505524 | 0.64 | ALDH1A1 (0.45) | CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034925-B1 | 5-(DIHYDROXYPHENOXY) TETRAZOLES AS SWEETENERS | ELI LILLY AND COMPANY (US) | 1983-05-04 | — | — | EP | claimed |
| US-4356207-A | Sweetening with 5-(dihydroxyphenoxy) tetrazoles | ELI LILLY AND COMPANY (US) | 1982-10-26 | — | — | US | claimed |
| US-4309446-A | 5-(Dihydroxyphenoxy)tetrazoles and use as sweeteners for medical compositions | ELI LILLY AND COMPANY (US) | 1982-01-05 | — | — | US | claimed |
| EP-0034925-A1 | 5-(Dihydroxyphenoxy) tetrazoles as sweeteners | ELI LILLY AND COMPANY (US) | 1981-09-02 | — | — | EP | claimed |
| EP-0034925-B1 | 5-(DIHYDROXYPHENOXY) TETRAZOLES AS SWEETENERS | ELI LILLY AND COMPANY (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4356207-A | Sweetening with 5-(dihydroxyphenoxy) tetrazoles | ELI LILLY AND COMPANY (US) | 1982-10-26 | — | — | US | disclosed |
| US-4309446-A | 5-(Dihydroxyphenoxy)tetrazoles and use as sweeteners for medical compositions | ELI LILLY AND COMPANY (US) | 1982-01-05 | — | — | US | disclosed |
| US-4297516-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0034925-A1 | 5-(Dihydroxyphenoxy) tetrazoles as sweeteners | ELI LILLY AND COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| EP-0007589-A1 | Insecticide agents comprising carbamate as active ingredient and triazole derivatives as synergists | BASF Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |