Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344731 | 0.96 | LMNA (0.52) | LMNAALDH1A1TSHR | |
| Ethylene SCHEMBL11209176 | 0.92 | LMNA (0.48) | LMNAALDH1A1TSHR | |
| Butane SCHEMBL9544063 | 0.87 | LMNA (0.43) | LMNAALDH1A1TSHR | |
| Butane SCHEMBL11232709 | 0.85 | LMNA (0.55) | LMNAALDH1A1 | |
| Butanal SCHEMBL264581 | 0.83 | ALDH1A1 (0.57) | LMNAALDH1A1TSHR | |
| Butanal SCHEMBL11750341 | 0.83 | ALDH1A1 (0.57) | LMNAALDH1A1TSHR | |
| SCHEMBL11485155 | 0.83 | LMNA (0.63) | LMNAALDH1A1TSHR | |
| SCHEMBL9657661 | 0.82 | LMNA (0.46) | LMNAALDH1A1TSHR | |
| SCHEMBL188914 | 0.81 | LMNA (0.60) | LMNAALDH1A1 | |
| Propionaldehyde SCHEMBL8906570 | 0.81 | LMNA (0.60) | LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110896-A | TRIPEPTIDYL DERIVATIVES HAVING A MERCAPTO OR ACYLTHIO GROUP AND WHICH ARE AMIDES; UTILITY AS MATRIX METALLOPROTEASE OR TNF INHIBITORS | DARWIN DISCOVERY, LTD. (GB) | 2000-08-29 | — | — | US | disclosed |