Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL11209176 | 0.96 | LMNA (0.48) | LMNAALDH1A1TSHR | |
| Butane SCHEMBL8184201 | 0.96 | LMNA (0.48) | LMNAALDH1A1TSHR | |
| SCHEMBL11485155 | 0.86 | LMNA (0.63) | LMNAALDH1A1TSHRTHRB | |
| SCHEMBL9657661 | 0.86 | LMNA (0.46) | LMNAALDH1A1TSHR | |
| SCHEMBL188914 | 0.84 | LMNA (0.60) | LMNAALDH1A1THRB | |
| Butane SCHEMBL9544063 | 0.83 | LMNA (0.43) | LMNAALDH1A1TSHR | |
| Butanal SCHEMBL264581 | 0.82 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRTHRB | |
| Glutaral SCHEMBL7174412 | 0.82 | LMNA (0.57) | LMNAALDH1A1TSHRTHRB | |
| Butanal SCHEMBL11750341 | 0.82 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRTHRB | |
| Butane SCHEMBL11232709 | 0.80 | LMNA (0.55) | LMNAALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826000-B1 | PEPTIDE COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION AND THEIR THERAPEUTIC USES | DARWIN DISCOVERY LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-0826000-A1 | PEPTIDE COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION AND THEIR THERAPEUTIC USES | Chiroscience Limited (GB) | 1998-03-04 | — | — | EP | disclosed |
| US-5656260-A | CONSISTS OF (3Z,,6Z)DODECADIENE-12-OLIDE AND 13-METHYL-(3Z,5Z)-13-OLIDE TOGETHER WITH FUNGAL VOLATILE SELECTED FROM 1-OCTEN-3-OL, 3-OCTANOL, 3-METHYLBUTANOL; EFFECTIVE TRAP FOR OKRYZAEPHILUS SURINAMENSIS BETTLE | THE MINISTER OF AGRICULTURE FISHERIES AND FOOD IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE U.K. OF GT. BRITAIN AND N. IRELAND (GB) | 1997-08-12 | — | — | US | disclosed |
| WO-1996035714-A1 | PEPTIDE COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION AND THEIR THERAPEUTIC USES | CHIROSCIENCE LIMITED (GB) | 1996-11-14 | — | — | WO | disclosed |