Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302858 | 0.79 | NOS3 (0.35) | NOS3NOS1NOS2ALDH1A1CYP3A4 | |
| SCHEMBL8687196 | 0.78 | TSHR (0.35) | TSHRKDM4ECYP3A4 | |
| SCHEMBL6472858 | 0.78 | TSHR (0.35) | TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL8692425 | 0.75 | ALDH1A1 (0.35) | TSHRKDM4EPOLBALDH1A1CYP3A4 | |
| SCHEMBL4653754 | 0.75 | TSHR (0.47) | TSHR | |
| SCHEMBL8692381 | 0.75 | MAPT (0.35) | TSHRMAPT | |
| SCHEMBL15788762 | 0.73 | TSHR (0.38) | TSHRKDM4EPOLBAPOBEC3GALDH1A1 | |
| SCHEMBL8689374 | 0.71 | KDM4E (0.45) | TSHRKDM4E | |
| SCHEMBL8692199 | 0.71 | MAPT (0.34) | TSHRPOLBPIK3CGSMN1; SMN2MAPT | |
| SCHEMBL8687585 | 0.71 | ALDH1A1 (0.40) | TSHRKDM4EPOLBPIK3CGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015083-B1 | PYROMELLITIC DIIMIDE COMPLEXES, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE IN IMPROVING THE FEED EFFICIENCY OF RUMINANTS | MERCK & CO. INC. (US) | 1982-12-29 | — | — | EP | claimed |
| US-4411690-A | Fused [1,2,4]oxadiazolylidenebenzenesulfonamides and their use as herbicides and plant growth regulants | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-10-25 | — | — | US | disclosed |
| EP-0058476-A2 | Fused (1,2,4) oxadiazolylidenebenzenesulfonamides and their use as herbicides and plant growth regulants | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-25 | — | — | EP | disclosed |
| EP-0057546-A2 | Sulfonylurea N-oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |