Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403072 | 0.82 | ALDH1A1 (0.36) | ALDH1A1NPC1RAB9APDE2APOLB | |
| SCHEMBL7640097 | 0.80 | ALDH1A1 (0.33) | ALDH1A1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL8687585 | 0.80 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9APOLBLMNA | |
| SCHEMBL8692199 | 0.80 | MAPT (0.34) | POLBTSHRSMN1; SMN2PIK3CACYP1A2 | |
| SCHEMBL8686884 | 0.80 | NUDT1 (0.54) | RECQLCYP1A2 | |
| SCHEMBL8692203 | 0.78 | MAPT (0.37) | ALDH1A1NPC1RAB9APOLBLMNA | |
| SCHEMBL8689288 | 0.76 | MEN1 (0.38) | ALDH1A1NPC1RAB9APOLBLMNA | |
| SCHEMBL11209326 | 0.75 | NOS3 (0.38) | ALDH1A1NPC1RAB9APOLBTSHR | |
| SCHEMBL6832179 | 0.73 | KMT2A (0.42) | ALDH1A1NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL8692276 | 0.73 | NUDT1 (0.50) | ALDH1A1RAB9ALMNAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760043-A | USING 2-AMINOPYRIDINE-3-OXIDE | L'OREAL (FR) | 1998-06-02 | — | — | US | disclosed |
| US-5610302-A | TREATMENT OF DISEASES OF SCALP DERMATITIS | L'OREAL (FR) | 1997-03-11 | — | — | US | disclosed |
| US-4411690-A | Fused [1,2,4]oxadiazolylidenebenzenesulfonamides and their use as herbicides and plant growth regulants | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-10-25 | — | — | US | disclosed |
| EP-0058476-A2 | Fused (1,2,4) oxadiazolylidenebenzenesulfonamides and their use as herbicides and plant growth regulants | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-25 | — | — | EP | disclosed |
| EP-0057546-A2 | Sulfonylurea N-oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |