Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692425 | 0.80 | ALDH1A1 (0.35) | PIK3CAMEN1CYP1A2POLBKMT2A | |
| SCHEMBL8687585 | 0.76 | ALDH1A1 (0.40) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL6398005 | 0.76 | MAPT (0.34) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL6832308 | 0.75 | TLR8 (0.40) | TLR8CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL8692203 | 0.73 | MAPT (0.37) | MAPTMEN1CYP1A2POLBKMT2A | |
| SCHEMBL8689288 | 0.72 | MEN1 (0.38) | MAPTMEN1CYP1A2POLBCYP2C9 | |
| SCHEMBL8686884 | 0.72 | NUDT1 (0.54) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11209326 | 0.71 | NOS3 (0.38) | MAPTPIK3CGPOLBSMN1; SMN2TSHR | |
| SCHEMBL8692276 | 0.69 | NUDT1 (0.50) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6832179 | 0.69 | KMT2A (0.42) | MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760043-A | USING 2-AMINOPYRIDINE-3-OXIDE | L'OREAL (FR) | 1998-06-02 | — | — | US | disclosed |
| US-5610302-A | TREATMENT OF DISEASES OF SCALP DERMATITIS | L'OREAL (FR) | 1997-03-11 | — | — | US | disclosed |