Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27824395 | 1.00 | CTSK (0.58) | CTSKCTSSCTSBCTSLS1PR4 | |
| SCHEMBL18257521 | 0.92 | CTSB (0.55) | CTSKCTSB | |
| SCHEMBL7119787 | 0.92 | CTSK (0.56) | CTSKCTSSCTSBCTSLS1PR4 | |
| SCHEMBL11682299 | 0.92 | LTA4H (0.57) | CTSKCTSB | |
| SCHEMBL11683261 | 0.92 | LTA4H (0.57) | CTSKCTSB | |
| SCHEMBL11680813 | 0.92 | LTA4H (0.57) | CTSKCTSB | |
| SCHEMBL22475577 | 0.92 | LTA4H (0.57) | CTSKCTSB | |
| SCHEMBL20881521 | 0.92 | LTA4H (0.57) | CTSKCTSB | |
| SCHEMBL21244283 | 0.92 | CTSB (0.55) | CTSKCTSB | |
| SCHEMBL16984879 | 0.92 | CTSB (0.55) | CTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102329376-B | Cyclo(phenylalanine-N-methylleucyl-leucyl-N-methylleucyl-leucyl), and synthesis method and application thereof | UNIV JINAN | 2013-07-10 | — | — | CN | claimed |
| CN-102329376-A | Cyclo(phenylalanine-N-methylleucyl-leucyl-N-methylleucyl-leucyl), and synthesis method and application thereof | UNIV JINAN | 2012-01-25 | — | — | CN | claimed |
| US-20150218212-A1 | FLUORINATED EPOXYKETONE-BASED TETRAPEPTIDE COMPOUNDS AND USES THEREOF AS PROTEASOME INHIBITORS | FLUORINOV PHARMA INC. (CA) | 2015-08-06 | — | — | US | disclosed |
| CN-102329376-B | Cyclo(phenylalanine-N-methylleucyl-leucyl-N-methylleucyl-leucyl), and synthesis method and application thereof | UNIV JINAN | 2013-07-10 | — | — | CN | disclosed |
| CN-102329376-A | Cyclo(phenylalanine-N-methylleucyl-leucyl-N-methylleucyl-leucyl), and synthesis method and application thereof | UNIV JINAN | 2012-01-25 | — | — | CN | disclosed |
| US-4382889-A | Epoxysuccinic acid derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| US-4333879-A | CALCIUM-ACTIVATED NEUTRAL THIOLPROTEASE INHIBITOR USED IN THE TREATMENT OF MUSCULAR DYSTROPHY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1982-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218212-A1 | FLUORINATED EPOXYKETONE-BASED TETRAPEPTIDE COMPOUNDS AND USES THEREOF AS PROTEASOME INHIBITORS | PSMA1, PSMB1, PSMB11 | CTSK 137/4885CTSS 1820/4885CTSB 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.