Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208112 | 1.00 | LMNA (0.48) | LMNAL3MBTL1PAX8USP2SLCO1B1 | |
| SCHEMBL2225961 | 1.00 | LMNA (0.48) | LMNAL3MBTL1PAX8USP2SLCO1B1 | |
| SCHEMBL7149767 | 1.00 | LMNA (0.48) | LMNAL3MBTL1PAX8USP2SLCO1B1 | |
| SCHEMBL7145241 | 1.00 | LMNA (0.48) | LMNAL3MBTL1PAX8USP2SLCO1B1 | |
| SCHEMBL186217 | 1.00 | LMNA (0.48) | LMNAL3MBTL1PAX8USP2SLCO1B1 | |
| SCHEMBL1548302 | 0.93 | LMNA (0.52) | LMNAL3MBTL1PAX8USP2SLCO1B1 | |
| SCHEMBL3116850 | 0.93 | LMNA (0.52) | LMNAL3MBTL1PAX8USP2SLCO1B1 | |
| SCHEMBL2228073 | 0.93 | LMNA (0.52) | LMNAL3MBTL1PAX8USP2SLCO1B1 | |
| SCHEMBL22963142 | 0.93 | LMNA (0.52) | LMNAL3MBTL1PAX8USP2SLCO1B1 | |
| SCHEMBL2066243 | 0.93 | LMNA (0.52) | LMNAL3MBTL1PAX8USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002588-B1 | PLEUROMUTILIN GLYCOSIDE DERIVATIVES, FORMULATIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1983-04-06 | — | — | EP | claimed |