SCHEMBL186217

SCHEMBL186217

N[C@@H](C=O)[C@H](O)[C@H](O)CO

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PAX8 Q06710 1/20 0.47
USP2 O75604 1/20 0.46
SLCO1B1 Q9Y6L6 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
AKR1B1 P15121 1/20 0.42
PDE4A P27815 1/20 0.39
KDM4E B2RXH2 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11208112 1.00 LMNA (0.48) LMNAL3MBTL1PAX8USP2SLCO1B1
SCHEMBL11209579 1.00 LMNA (0.48) LMNAL3MBTL1PAX8USP2SLCO1B1
SCHEMBL2225961 1.00 LMNA (0.48) LMNAL3MBTL1PAX8USP2SLCO1B1
SCHEMBL7149767 1.00 LMNA (0.48) LMNAL3MBTL1PAX8USP2SLCO1B1
SCHEMBL7145241 1.00 LMNA (0.48) LMNAL3MBTL1PAX8USP2SLCO1B1
SCHEMBL1548302 0.93 LMNA (0.52) LMNAL3MBTL1PAX8USP2SLCO1B1
SCHEMBL3116850 0.93 LMNA (0.52) LMNAL3MBTL1PAX8USP2SLCO1B1
SCHEMBL2228073 0.93 LMNA (0.52) LMNAL3MBTL1PAX8USP2SLCO1B1
SCHEMBL22963142 0.93 LMNA (0.52) LMNAL3MBTL1PAX8USP2SLCO1B1
SCHEMBL2066243 0.93 LMNA (0.52) LMNAL3MBTL1PAX8USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119846229-A Biomarker for detecting diabetic macular edema, kit and application thereof 首都医科大学附属北京同仁医院 2025-04-18 CN claimed
EP-3126517-B1 MODIFIED CYTOSINE POLYNUCLEOTIDE OLIGOMERS AND METHODS CEPHEID (US) 2019-10-23 EP claimed
CN-106460058-B Modified cytosine polynucleotide oligomers and methods 赛沛 2019-07-09 CN claimed
EP-3126372-B1 MODIFIED THYMINE POLYNUCLEOTIDE OLIGOMERS AND METHODS CEPHEID (US) 2019-02-06 EP claimed
CN-106459128-B Modified thymine polynucleotide oligomers and methods 赛沛 2018-05-29 CN claimed
US-9598456-B2 Modified cytosine polynucleotide oligomers and methods CEPHEID (US) 2017-03-21 US claimed
US-9598455-B2 Modified thymine polynucleotide oligomers and methods CEPHEID (US) 2017-03-21 US claimed
US-20120076781-A1 METHODS OF TREATING CANCERS WITH HER3 ANTISENSE OLIGONUCLEOTIDES SANTARIS PHARMA A/S (DK) 2012-03-29 US claimed
CN-102395374-A Methods of treating cancers with her3 antisense oligonucleotides ENZON PHARMACEUTICALS INC 2012-03-28 CN claimed
EP-2419110-A1 METHODS OF TREATING CANCERS WITH HER3 ANTISENSE OLIGONUCLEOTIDES Enzon Pharmaceuticals, Inc. (US) 2012-02-22 EP claimed
CN-1822856-B HCV vaccines INTERCELL AG 2010-04-28 CN claimed
US-20090203137-A1 COMPOUNDS FOR THE MODULATION OF BETA-CATENIN EXPRESSION SANTARIS PHARMA A/S (DK) 2009-08-13 US claimed
US-20090192110-A1 RNA ANTAGONIST COMPOUNDS FOR THE MODULATION OF PIK3CA EXPRESSION SANTARIS PHARMA A/S 2009-07-30 US claimed
US-20090181916-A1 LNA ANTAGONISTS TARGETING THE ANDROGEN RECEPTOR SANTARIS PHARMA A/S (DK) 2009-07-16 US claimed
US-20090005335-A1 COMPOUNDS FOR THE MODULATION OF BETA-CATENIN EXPRESSION SANTARIS PHARMA A/S (DK) 2009-01-01 US claimed
US-20080318894-A1 RNA ANTAGONIST COMPOUNDS FOR THE MODULATION OF HER3 SANTARIS PHARMA A/S (DK) 2008-12-25 US claimed
CN-1822856-A HCV vaccines INTERCELL AG (AT) 2006-08-23 CN claimed
CN-1771054-A Improved vaccines INTERCELL AG (AT) 2006-05-10 CN claimed
CN-1434723-A Immunostimulatory oligodeoxynucleotides CISTEM BIOTECHNOLOGIES GMBH (AT) 2003-08-06 CN claimed
US-5190783-A Dietetics NABISCO, INC. (US) 1993-03-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005335-A1 COMPOUNDS FOR THE MODULATION OF BETA-CATENIN EXPRESSION CTNNB1, CTNNA1, WNT1 LMNA 673/4885L3MBTL1 741/4885PAX8 1961/4885
US-20090192110-A1 RNA ANTAGONIST COMPOUNDS FOR THE MODULATION OF PIK3CA EXPRESSION PIK3CA, PIK3R4, PIK3R5 LMNA 3031/4885L3MBTL1 992/4885PAX8 3436/4885
US-20090203137-A1 COMPOUNDS FOR THE MODULATION OF BETA-CATENIN EXPRESSION CTNNB1, CTNNA1, WNT1 LMNA 673/4885L3MBTL1 741/4885PAX8 1961/4885
US-20090181916-A1 LNA ANTAGONISTS TARGETING THE ANDROGEN RECEPTOR AR, ESRRB, ESRRA LMNA 1452/4885L3MBTL1 627/4885PAX8 868/4885
US-20120076781-A1 METHODS OF TREATING CANCERS WITH HER3 ANTISENSE OLIGONUCLEOTIDES ERBB3, ERBB2, EGFR LMNA 4174/4885L3MBTL1 1420/4885PAX8 1785/4885
US-20080318894-A1 RNA ANTAGONIST COMPOUNDS FOR THE MODULATION OF HER3 ERBB3, EGFR, ERBB2 LMNA 3823/4885L3MBTL1 1063/4885PAX8 3039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.