SCHEMBL11210079

SCHEMBL11210079

O=[N+]([O-])c1ccc(OS(=O)(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.57
CA2 P00918 5/20 0.57
CA9 Q16790 4/20 0.57
ALDH1A1 P00352 3/20 0.49
HSP90AA1 P07900 1/20 0.49
HTT P42858 1/20 0.49
CA12 O43570 3/20 0.44
GAA P10253 1/20 0.42
HSPB1 P04792 1/20 0.42
CA7 P43166 2/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA13 Q8N1Q1 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
LMNA P02545 4/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28640874 0.80 CA1 (0.57) CA1CA2CA9ALDH1A1HSP90AA1
SCHEMBL866411 0.77 CA1 (0.67) CA1CA2CA9ALDH1A1HSP90AA1
SCHEMBL4826239 0.77 CA1 (0.67) CA1CA2CA9ALDH1A1HSP90AA1
SCHEMBL2239682 0.77 ALDH1A1 (0.63) CA1CA2CA9ALDH1A1HSP90AA1
SCHEMBL2237370 0.77 ALDH1A1 (0.63) CA1CA2CA9ALDH1A1HSP90AA1
SCHEMBL866410 0.76 CA1 (0.71) CA1CA2CA9ALDH1A1HSP90AA1
Sulfuric Acid SCHEMBL3198737 0.75 CA1 (0.65) CA1CA2CA9ALDH1A1HSP90AA1
SCHEMBL14594621 0.75 HTT (0.62) CA1CA2CA9ALDH1A1HSP90AA1
SCHEMBL7527679 0.74 CA1 (0.62) CA1CA2CA9ALDH1A1HSP90AA1
Hydrazine SCHEMBL28200768 0.74 CA1 (0.68) CA1CA2CA9ALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0021215-B1 PSEUDOTRISACCHARIDES, THEIR PREPARATION AND USE AS MEDICAMENTS BAYER AG (DE) 1983-07-13 EP disclosed
EP-0021215-A1 Pseudotrisaccharides, their preparation and use as medicaments BAYER AG (DE) 1981-01-07 EP disclosed