Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | MLYCD | O95822 | 2/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27878081 | 0.98 | KMT2A (0.50) | KMT2AMEN1CDK4CCND1MLYCD | |
| SCHEMBL11210779 | 0.90 | KMT2A (0.56) | KMT2AMEN1CDK4CCND1MLYCD | |
| SCHEMBL10795881 | 0.90 | HDAC4 (0.54) | CDK4CCND1MLYCDPDK2HDAC6 | |
| SCHEMBL8070639 | 0.85 | HDAC6 (0.54) | KMT2AMEN1CDK4CCND1MLYCD | |
| SCHEMBL8641718 | 0.84 | HDAC6 (0.59) | KMT2AMEN1CDK4CCND1MLYCD | |
| SCHEMBL1006489 | 0.84 | NAMPT (0.54) | KMT2AMEN1CDK4CCND1MLYCD | |
| SCHEMBL6598473 | 0.84 | KMT2A (0.51) | KMT2AMEN1CDK4CCND1MLYCD | |
| SCHEMBL11210960 | 0.84 | HDAC6 (0.59) | KMT2AMEN1CDK4CCND1MLYCD | |
| SCHEMBL3362719 | 0.83 | KMT2A (0.55) | KMT2AMEN1CDK4CCND1MLYCD | |
| SCHEMBL11208187 | 0.83 | AKR1C3 (0.50) | KMT2AMEN1L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103608350-B | Triazolopyridine compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-25 | — | — | CN | claimed |
| CN-103608350-A | Triazolopyridine compounds | BAYER IP GMBH | 2014-02-26 | — | — | CN | claimed |
| US-20060058553-A1 | Novel bicyclic hydroxamates as inhibitors of histone deacetylase | AXYS PHARMACEUTICALS, INC. (US) | 2006-03-16 | — | — | US | claimed |
| US-20250074887-A1 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF | Sea Pharmaceuticals LLC. (US) | 2025-03-06 | — | — | US | disclosed |
| WO-2023130008-A2 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF | SEA PHARMACEUTICALS LLC (US) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023130008-A2 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF | SEA PHARMACEUTICALS LLC (US) | 2023-07-06 | — | — | WO | disclosed |
| EP-3661941-B1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | disclosed |
| US-11492340-B2 | Heteroaromatic electrophiles and methods of using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2022-11-08 | — | — | US | disclosed |
| US-20220204472-A1 | HETEROAROMATIC ELECTROPHILES AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2022-06-30 | — | — | US | disclosed |
| EP-3275440-B1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | NAT CT GERIATRICS & GERONTOLOGY (JP) | 2022-05-04 | — | — | EP | disclosed |
| US-10633403-B2 | N-heterocyclic phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA (US) | 2020-04-28 | — | — | US | disclosed |
| US-5478856-A | Styrene derivatives and salts thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| US-5478851-A | Hyperglycemic agent and antilipemic agent | BEECHAM GROUP PLC (GB) | 1995-12-26 | — | — | US | disclosed |
| US-5399577-A | Lipoxygenase and cyclooxygenase inhibitor, antiasthma, antiinflammatory | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0633254-A1 | NOVEL ISOXAZOLE DERIVATIVE AND SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0623603-A1 | STYRENE DERIVATIVE AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |
| EP-0555264-A1 | NOVEL COMPOUNDS | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007850-A1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | disclosed |
| US-4874857-A | FIBER-REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-17 | — | — | US | disclosed |
| US-4017522-A | MICROBIOCIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492340-B2 | Heteroaromatic electrophiles and methods of using thereof | ACHE, BCHE, CHAT | KMT2A 1480/4885MEN1 4083/4885CDK4 1913/4885 |
| US-20250074887-A1 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF | GABRQ, GRIK5, CYP3A7 | KMT2A 1192/4885MEN1 1622/4885CDK4 3682/4885 |
| US-20220204472-A1 | HETEROAROMATIC ELECTROPHILES AND METHODS OF USING THEREOF | ACHE, BCHE, CHAT | KMT2A 1480/4885MEN1 4083/4885CDK4 1913/4885 |
| US-10633403-B2 | N-heterocyclic phosphines | NANP, PPIP5K2, PHPT1 | KMT2A 2508/4885MEN1 469/4885CDK4 252/4885 |
| US-20060058553-A1 | Novel bicyclic hydroxamates as inhibitors of histone deacetylase | HDAC1, HDAC2, HDAC11 | KMT2A 100/4885MEN1 4206/4885CDK4 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.