Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210779 | 0.88 | KMT2A (0.56) | MLYCDKMT2ACDK4CCND1MEN1 | |
| SCHEMBL1003843 | 0.85 | ADRA2C (0.53) | MLYCDKMT2ACDK4CCND1MEN1 | |
| SCHEMBL22537874 | 0.83 | CDK4 (0.49) | MLYCDKMT2ACDK4CCND1MEN1 | |
| SCHEMBL8641718 | 0.82 | HDAC6 (0.59) | MLYCDKMT2ACDK4CCND1MEN1 | |
| SCHEMBL1004454 | 0.82 | KMT2A (0.51) | MLYCDKMT2ACDK4CCND1MEN1 | |
| SCHEMBL11210960 | 0.82 | HDAC6 (0.59) | MLYCDKMT2ACDK4CCND1MEN1 | |
| SCHEMBL6598473 | 0.82 | KMT2A (0.51) | MLYCDKMT2ACDK4CCND1MEN1 | |
| SCHEMBL1006489 | 0.82 | NAMPT (0.54) | MLYCDKMT2ACDK4CCND1MEN1 | |
| SCHEMBL11248980 | 0.81 | ADRA2C (0.63) | MLYCDKMT2ACDK4CCND1MEN1 | |
| SCHEMBL13585636 | 0.81 | MLYCD (0.50) | MLYCDKMT2ACDK4CCND1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017981-A1 | AZACYCLIC DERIVATIVES | DR. LO. ZAMBELETTI S.P.A. (IT) | 1991-11-28 | — | — | WO | disclosed |