Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211662 | 0.92 | SIGMAR1 (0.48) | HDAC3HDAC1HDAC2NCOR2BCHE | |
| SCHEMBL11209448 | 0.89 | BCHE (0.48) | BCHEMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL11210926 | 0.84 | BCHE (0.52) | BCHEMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL11208739 | 0.83 | BCHE (0.50) | BCHEMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL11212327 | 0.81 | BCHE (0.51) | BCHEMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL11208063 | 0.81 | FFAR1 (0.43) | SIGMAR1MAPK1 | |
| SCHEMBL11283415 | 0.78 | HDAC3 (0.43) | HDAC3HDAC1HDAC2SIGMAR1 | |
| SCHEMBL11208145 | 0.77 | FFAR1 (0.46) | BCHEMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL11209589 | 0.77 | TDP1 (0.50) | BCHEMEN1KMT2APOLBMAPK1 | |
| SCHEMBL11208647 | 0.77 | SGMS2 (0.48) | BCHEMEN1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051196-B1 | 4-BENZYLOXY-ALPHA-TRICHLOROMETHYLBENZYL AMINES, PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |