Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208647 | 0.79 | SGMS2 (0.48) | L3MBTL1MAPTNPC1RAB9ABCHE | |
| SCHEMBL11209448 | 0.79 | BCHE (0.48) | L3MBTL1MAPTNPC1RAB9ABCHE | |
| SCHEMBL11211010 | 0.77 | HDAC3 (0.48) | BCHELMNAMEN1KMT2APOLB | |
| SCHEMBL11210926 | 0.77 | BCHE (0.52) | RAB9ABCHELMNASMN1; SMN2MEN1 | |
| SCHEMBL11208739 | 0.76 | BCHE (0.50) | L3MBTL1MAPTNPC1RAB9ABCHE | |
| SCHEMBL3423751 | 0.75 | TDP1 (0.74) | TDP1L3MBTL1BCHELMNAMEN1 | |
| SCHEMBL11211662 | 0.75 | SIGMAR1 (0.48) | TDP1L3MBTL1HTTNPC1RAB9A | |
| SCHEMBL11212327 | 0.74 | BCHE (0.51) | BCHELMNAMEN1KMT2APOLB | |
| SCHEMBL28508353 | 0.71 | L3MBTL1 (0.53) | TDP1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL11206231 | 0.71 | MAOB (0.54) | L3MBTL1MAPTRAB9ABCHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051196-B1 | 4-BENZYLOXY-ALPHA-TRICHLOROMETHYLBENZYL AMINES, PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |