Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207912 | 0.90 | MAPT (0.47) | SGMS2MAPTALDH1A1KMT2APOLB | |
| SCHEMBL11279957 | 0.88 | RAB9A (0.44) | SGMS2MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL11209589 | 0.79 | TDP1 (0.50) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL11209448 | 0.79 | BCHE (0.48) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL11282164 | 0.77 | PTPRZ1 (0.38) | SGMS2MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL11210926 | 0.77 | BCHE (0.52) | MEN1KMT2APOLBBCHECYP1A2 | |
| SCHEMBL11211010 | 0.77 | HDAC3 (0.48) | MEN1KMT2APOLBBCHECYP1A2 | |
| SCHEMBL11208739 | 0.76 | BCHE (0.50) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL3425734 | 0.75 | BCHE (0.71) | ALDH1A1MEN1KMT2ABCHEMAPK1 | |
| SCHEMBL11211662 | 0.75 | SIGMAR1 (0.48) | L3MBTL1MEN1KMT2ABCHECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051196-B1 | 4-BENZYLOXY-ALPHA-TRICHLOROMETHYLBENZYL AMINES, PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |