Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3185113 | 0.91 | THRB (0.43) | THRBKMT2ACYP1A2MEN1ALDH1A1 | |
| SCHEMBL349876 | 0.84 | THRB (0.54) | THRBKMT2ACYP1A2MEN1ALDH1A1 | |
| SCHEMBL31282824 | 0.79 | ALDH1A1 (0.52) | THRBKMT2ACYP1A2MEN1ALDH1A1 | |
| SCHEMBL7444135 | 0.78 | LMNA (0.46) | THRBKMT2ACYP1A2MEN1ALDH1A1 | |
| SCHEMBL349825 | 0.77 | GLRA1 (0.38) | GLRA1SLC6A9OR51E2HIF1ASMN1; SMN2 | |
| SCHEMBL11037692 | 0.76 | ALDH1A1 (0.52) | THRBKMT2ACYP1A2MEN1ALDH1A1 | |
| SCHEMBL28500432 | 0.76 | ALDH1A1 (0.52) | THRBKMT2ACYP1A2MEN1ALDH1A1 | |
| SCHEMBL30745968 | 0.75 | ALDH1A1 (0.39) | THRBKMT2ACYP1A2MEN1ALDH1A1 | |
| SCHEMBL1309958 | 0.74 | GRM8 (0.57) | THRBKMT2ACYP1A2MEN1ALDH1A1 | |
| SCHEMBL20338605 | 0.74 | PPARG (0.53) | KMT2ACYP1A2MEN1ALDH1A1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374062-A | ASSYMETRICAL HYDROGENATION OF DEHYDROPEPTIDES USING A PHODIUM COMPLEX CATALYST | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1983-02-15 | — | — | US | disclosed |