Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866123 | 0.86 | HSD11B1 (0.57) | HTR6CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL17774708 | 0.82 | HTR6 (0.52) | HTR6CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL228959 | 0.81 | KIF18A (0.57) | HTR6CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL29712886 | 0.81 | HTR6 (0.66) | HTR6CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL9070302 | 0.81 | HTR6 (0.66) | HTR6CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL11321170 | 0.79 | MEN1 (0.46) | CYP3A4CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL13309929 | 0.79 | KIF18A (0.58) | HTR6CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL17774551 | 0.79 | POLB (0.69) | HTR6MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11592806 | 0.79 | HTR6 (0.56) | HTR6CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL10656611 | 0.79 | MEN1 (0.63) | HTR6CYP3A4CYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |
| US-4118384-A | DIAZOTIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |