Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309929 | 0.96 | KIF18A (0.58) | KIF18AKDM4EALDH1A1TSHRCNR2 | |
| SCHEMBL9475478 | 0.88 | ALDH1A1 (0.60) | KIF18AKDM4EALDH1A1TSHRCNR2 | |
| SCHEMBL13309937 | 0.85 | HTT (0.51) | KIF18AKDM4EMCL1 | |
| SCHEMBL13309930 | 0.85 | KIF18A (0.48) | KIF18AKDM4EALDH1A1TSHRCNR2 | |
| SCHEMBL2462163 | 0.85 | KIF18A (0.61) | KIF18AALDH1A1CNR2HTR6AKR1B1 | |
| SCHEMBL227808 | 0.85 | KIF18A (0.57) | KIF18AKDM4EALDH1A1CNR2HTR6 | |
| SCHEMBL13309933 | 0.84 | ITGA1 (0.54) | KIF18AKDM4ECNR2MAPK1 | |
| SCHEMBL5068459 | 0.83 | MCL1 (0.57) | KDM4EALDH1A1TSHRALOX15L3MBTL1 | |
| SCHEMBL12696990 | 0.81 | POLB (0.54) | ALDH1A1TSHRCNR2ALOX15L3MBTL1 | |
| SCHEMBL11212056 | 0.81 | HTR6 (0.61) | KIF18AKDM4EALDH1A1CNR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519554-B1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | DU PONT (US) | 2016-03-16 | — | — | EP | disclosed |
| US-8609804-B2 | Polyarylene polymers and processes for preparing | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-12-17 | — | — | US | disclosed |
| US-20120322973-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120322973-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120322973-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-20 | — | — | US | disclosed |
| EP-2519554-A2 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E.I. Du Pont De Nemours And Company (US) | 2012-11-07 | — | — | EP | disclosed |
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-05 | — | — | US | disclosed |
| WO-2011090705-A2 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011090705-A2 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-28 | — | — | WO | disclosed |
| US-20100105786-A1 | Method for Producing Polymer Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-1721922-A1 | METHOD FOR PRODUCING POLYMER COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2006-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | PCBP1, PARG, PARN | KIF18A 1958/4885KDM4E 2295/4885ALDH1A1 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.