Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534423 | 0.79 | MAPT (0.39) | MEN1NPC1MAPTRAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL11047993 | 0.78 | MAPT (0.38) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL2865383 | 0.71 | ACHE (0.46) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL11207252 | 0.71 | ALDH1A1 (0.33) | ALDH1A1CYP3A4THRBNQO2ACHE | |
| SCHEMBL9669331 | 0.69 | TYMS (0.45) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL27761307 | 0.67 | NQO2 (0.48) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL12964174 | 0.66 | KDM4E (0.42) | ALDH1A1MAPTKMT2AKDM4ETP53 | |
| SCHEMBL5984487 | 0.66 | ACHE (0.39) | ALDH1A1MAPTRAB9AKMT2AKDM4E | |
| SCHEMBL26130223 | 0.65 | MAP4K4 (0.34) | MEN1MAPTKMT2AIMPDH2BLM | |
| SCHEMBL11472339 | 0.65 | MAPT (0.53) | MEN1NPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010722-B1 | MONOAZO-COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-20 | — | — | EP | disclosed |
| US-4312807-A | HEAT RESISTANT PIGMENTS FOR POLYVINYL CHLORIDE AND POLYETHYLENE | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| EP-0010722-A1 | Monoazo-compounds, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-14 | — | — | EP | disclosed |