Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | MELK | Q14680 | 1/20 | 0.37 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865383 | 0.80 | ACHE (0.46) | PLAUNCF1ACHEALDH1A1HPGD | |
| SCHEMBL9669419 | 0.76 | SOS2 (0.39) | PLAUACHEALDH1A1HPGDHSD17B10 | |
| SCHEMBL9670587 | 0.74 | TYMS (0.49) | TYMSALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL9534423 | 0.72 | MAPT (0.39) | ACHECYP1A2KMT2AKDM4EGAA | |
| SCHEMBL10085320 | 0.72 | ACHE (0.58) | PLAUNCF1ACHEALDH1A1HPGD | |
| SCHEMBL14742902 | 0.72 | ALDH1A1 (0.59) | TYMSPLAUMETJAK2RPS6KA3 | |
| Hydrochloric Acid SCHEMBL11047993 | 0.71 | MAPT (0.38) | ACHECYP1A2KMT2AKDM4EGAA | |
| SCHEMBL9578558 | 0.71 | PRMT5 (0.49) | ALDH1A1HSD17B10CYP1A2CYP3A4TSHR | |
| SCHEMBL65699 | 0.70 | JAK2 (0.54) | TYMSJAK2RPS6KA3MELKSTK24 | |
| SCHEMBL29349435 | 0.70 | JAK2 (0.54) | TYMSJAK2RPS6KA3MELKSTK24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889855-A | ADMINISTERING GLUTAMATE ANTAGONIST TO INHIBIT HYPERACTIVITY OF EXCITATORY NEUROTRANSMITTERS | A/S FERROSAN (DK) | 1989-12-26 | — | — | US | claimed |
| EP-0283959-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-01-02 | — | — | EP | disclosed |
| US-4912108-A | Containing hydroxy substitution | A/S FERROSAN (DK) | 1990-03-27 | — | — | US | disclosed |
| US-4889855-A | ADMINISTERING GLUTAMATE ANTAGONIST TO INHIBIT HYPERACTIVITY OF EXCITATORY NEUROTRANSMITTERS | A/S FERROSAN (DK) | 1989-12-26 | — | — | US | disclosed |
| EP-0283959-A1 | Heterocyclic compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1988-09-28 | — | — | EP | disclosed |