Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4587893 | 0.85 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2PKMHPGDRAB9A | |
| SCHEMBL8702006 | 0.81 | CES2 (0.62) | ALDH1A1SMN1; SMN2PKMHPGDRAB9A | |
| SCHEMBL6989528 | 0.76 | RAB9A (0.61) | ALDH1A1SMN1; SMN2PKMRAB9AALOX12 | |
| SCHEMBL27905947 | 0.75 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2PKMHPGDRAB9A | |
| SCHEMBL27339507 | 0.74 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2PKMHPGDRAB9A | |
| SCHEMBL11525034 | 0.74 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2PKMHPGDRAB9A | |
| SCHEMBL3040275 | 0.74 | RAB9A (0.59) | ALDH1A1SMN1; SMN2PKMRAB9ANPC1 | |
| SCHEMBL6758983 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2PKMHPGDRAB9A | |
| SCHEMBL2969896 | 0.74 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2PKMHPGDRAB9A | |
| SCHEMBL140989 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | claimed |
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |