Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490925 | 0.89 | ALOX5 (0.62) | ALOX5NFKB1NFKB2RELATNKS2 | |
| SCHEMBL11212268 | 0.87 | ALOX5 (0.55) | ALOX5NFKB1NFKB2RELATNKS2 | |
| SCHEMBL14922486 | 0.84 | GAA (0.50) | ALOX5NFKB1NFKB2RELAOR51E2 | |
| SCHEMBL11215998 | 0.84 | ALDH1A1 (0.58) | ALOX5NFKB1ALDH1A1GAAGFER | |
| SCHEMBL5072092 | 0.82 | TRPV1 (0.54) | ALOX5NFKB1NFKB2RELATNKS2 | |
| SCHEMBL11214618 | 0.82 | GAA (0.44) | ALOX5ALDH1A1GAAGFERMAPT | |
| SCHEMBL28853057 | 0.82 | TRPV1 (0.54) | ALOX5NFKB1NFKB2RELATNKS2 | |
| SCHEMBL7283109 | 0.80 | ALDH1A1 (0.57) | ALOX5OR51E2ALDH1A1GAAGFER | |
| SCHEMBL3949236 | 0.80 | GAA (0.57) | ALOX5OR51E2ALDH1A1GAAGFER | |
| SCHEMBL9520560 | 0.79 | GAA (0.61) | ALDH1A1GAAGFERMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |