Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 13/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221894 | 0.83 | ABCC9 (0.41) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL11218301 | 0.73 | PGR (0.41) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL11212863 | 0.72 | PGR (0.42) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL11215869 | 0.65 | NOTUM (0.46) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL11461359 | 0.64 | ABCB1 (0.37) | ABCB1 | |
| SCHEMBL31103518 | 0.64 | NOS3 (0.44) | — | |
| SCHEMBL11444455 | 0.64 | ABCB1 (0.39) | ABCB1 | |
| SCHEMBL6103250 | 0.64 | PGR (0.47) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL16905573 | 0.63 | PGR (0.38) | ABCB1 | |
| SCHEMBL8984728 | 0.62 | PDK2 (0.50) | ABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333759-A | Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones | FISONS LIMITED (GB) | 1982-06-08 | — | — | US | claimed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | claimed |