Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16432838 | 0.86 | NOS3 (0.36) | NOS3NOS1NOS2PDE10ATRPM8 | |
| SCHEMBL30505752 | 0.85 | TRPM8 (0.37) | NOS3NOS1NOS2PDE10ATRPM8 | |
| SCHEMBL29131679 | 0.85 | TRPM8 (0.37) | NOS3NOS1NOS2PDE10ATRPM8 | |
| SCHEMBL29070262 | 0.84 | CYP1A2 (0.35) | NOS3NOS1NOS2CYP1A2CYP2C9 | |
| SCHEMBL29070263 | 0.82 | NOS2 (0.33) | NOS2CYP1A2CYP2C9HIF1A | |
| SCHEMBL23131526 | 0.79 | APOBEC3A (0.34) | NOS3NOS2PDE10AHTTRECQL | |
| SCHEMBL9953928 | 0.79 | NOS3 (0.41) | NOS3NOS1NOS2PDE10ACYP1A2 | |
| SCHEMBL31374320 | 0.79 | NOS3 (0.41) | NOS3NOS1NOS2PDE10ACYP1A2 | |
| SCHEMBL31442989 | 0.79 | TRPM8 (0.38) | NOS3NOS1NOS2PDE10ATRPM8 | |
| SCHEMBL31442991 | 0.79 | TRPM8 (0.38) | NOS3NOS1NOS2PDE10ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57062269-A | — | — | None | — | — | JP | disclosed |
| JP-S5762269-A | 2,3,5-TRISUBSTITUTED PYRAZINE DERIVATIVE | OGAWA KORYO KK | 1982-04-15 | — | — | JP | disclosed |