Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11171137 | 0.82 | THRB (0.35) | THRB | |
| SCHEMBL11177282 | 0.79 | HTT (0.33) | THRBIKBKBHTTALDH1A1MAPK1 | |
| SCHEMBL10385524 | 0.78 | THRB (0.36) | THRBHTTALDH1A1LMNA | |
| SCHEMBL7071732 | 0.75 | TSHR (0.39) | THRBHTTALDH1A1LMNA | |
| SCHEMBL10870996 | 0.75 | ALDH1A1 (0.44) | THRBALDH1A1 | |
| SCHEMBL937676 | 0.73 | ALDH1A1 (0.42) | THRBALDH1A1 | |
| SCHEMBL10606491 | 0.71 | THRB (0.38) | THRBALDH1A1 | |
| SCHEMBL10608315 | 0.71 | THRB (0.42) | THRBALDH1A1 | |
| SCHEMBL10718239 | 0.71 | LMNA (0.41) | THRBHTTALDH1A1LMNA | |
| SCHEMBL4758789 | 0.70 | THRB (0.37) | THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071395-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | claimed |
| US-4369298-A | Novel cured resin, process for production thereof, and lens composed of said resin from bis(alkyleneoxyphenyl)-diacrylate, bis(alkyleneoxyphenyl)diallyl ether, bis(alkyleneoxyphenyl)diallyl carbonate monomers | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1983-01-18 | — | — | US | disclosed |