Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066662 | 0.79 | AKR1B1 (0.38) | LMNATSHRCYP3A4ALDH1A1HPGD | |
| SCHEMBL31192373 | 0.79 | AKR1B1 (0.38) | LMNATSHRCYP3A4ALDH1A1HPGD | |
| SCHEMBL10385524 | 0.78 | THRB (0.36) | LMNAHTTTSHRTHRBALDH1A1 | |
| SCHEMBL11185498 | 0.78 | ELANE (0.36) | TSHRCYP3A4ALDH1A1MEN1GAA | |
| SCHEMBL11177282 | 0.73 | HTT (0.33) | LMNAHTTTHRBALDH1A1CASP1 | |
| SCHEMBL3157120 | 0.73 | L3MBTL1 (0.42) | LMNATSHRTHRBALDH1A1MEN1 | |
| SCHEMBL10385058 | 0.73 | KDM4E (0.44) | RORCTSHRCYP3A4THRBALDH1A1 | |
| SCHEMBL4906665 | 0.72 | LMNA (0.44) | LMNARORCTSHRALDH1A1MEN1 | |
| SCHEMBL10870996 | 0.71 | ALDH1A1 (0.44) | TSHRTHRBALDH1A1KMT2ACYP1A2 | |
| SCHEMBL9183227 | 0.71 | L3MBTL1 (0.44) | LMNATSHRALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4704006-A | HIGH REFRACTIVE INDEX, DYEABILITY, SOLVENT RESISTANCE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-11-03 | — | — | US | disclosed |
| EP-0142921-B1 | HALOGEN-CONTAINING RESIN LENS MATERIAL | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-08-26 | — | — | EP | disclosed |
| EP-0142921-A1 | Halogen-containing resin lens material | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-29 | — | — | EP | disclosed |