SCHEMBL11214366

SCHEMBL11214366

OCc1ccc(O)c(Cl)c1CO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 1/20 0.42
PDXK O00764 1/20 0.41
LMNA P02545 2/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HPGD P15428 2/20 0.37
HIF1A Q16665 2/20 0.37
IDO1 P14902 2/20 0.37
MEN1 O00255 1/20 0.37
SLC22A1 O15245 1/20 0.37
USP2 O75604 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPT P10636 1/20 0.37
HSPD1 P10809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30055353 0.81 CYP3A4 (0.37) CYP3A4MAPK1PDXKLMNAHTT
SCHEMBL11301238 0.81 CYP3A4 (0.37) CYP3A4MAPK1PDXKLMNAHTT
SCHEMBL207165 0.80 KDM4E (0.41) PDXKLMNAHTTSMN1; SMN2KDM4E
SCHEMBL30274440 0.76 CYP1A2 (0.43) CYP3A4PDXKLMNAHTTSMN1; SMN2
SCHEMBL1525478 0.76 APOBEC3G (0.43) PDXKLMNAHTTSMN1; SMN2KDM4E
SCHEMBL286423 0.74 CYP3A4 (0.41) CYP3A4MAPK1PDXKLMNAHTT
SCHEMBL31302207 0.74 TYR (0.40) LMNAHTTSMN1; SMN2KDM4ENPC1
Formaldehyde SCHEMBL11236931 0.74 PKM (0.38) PDXKLMNAHTTSMN1; SMN2KDM4E
SCHEMBL394136 0.74 TYR (0.40) LMNAHTTSMN1; SMN2KDM4ENPC1
SCHEMBL10748552 0.74 CA2 (0.39) CYP3A4LMNAHTTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0020541-B1 COATING POLYMERIZATION REACTORS WITH OLIGOMER COATINGS DERIVED FROM REACTION PRODUCTS OF SUBSTITUTED PHENOLS The B.F. GOODRICH Company (US) 1983-05-18 EP disclosed
EP-0020541-A1 COATING POLYMERIZATION REACTORS WITH OLIGOMER COATINGS DERIVED FROM REACTION PRODUCTS OF SUBSTITUTED PHENOLS. GOODRICH CO B F (US) 1981-01-07 EP disclosed
EP-0020541-A4 COATING POLYMERIZATION REACTORS WITH OLIGOMER COATINGS DERIVED FROM REACTION PRODUCTS OF SUBSTITUTED PHENOLS. GOODRICH CO B F (US) 1980-11-28 EP disclosed
WO-1980000801-A1 COATING POLYMERIZATION REACTORS WITH OLIGOMER COATINGS DERIVED FROM REACTION PRODUCTS OF SUBSTITUTED PHENOLS GOODRICH CO B F (US) 1980-05-01 WO disclosed
US-4200712-A Coating polymerization reactors with oligomer coatings derived from reaction products of substituted phenols THE B. F. GOODRICH COMPANY (US) 1980-04-29 US disclosed