Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11178753 | 0.82 | LMNA (0.52) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL6694830 | 0.81 | LMNA (1.00) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL137254 | 0.74 | LMNA (0.59) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL8946061 | 0.74 | LMNA (0.59) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL1642674 | 0.72 | LMNA (0.68) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL3833573 | 0.72 | LMNA (0.68) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL2754142 | 0.71 | LMNA (0.55) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL10394940 | 0.71 | LMNA (0.66) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL8092219 | 0.69 | LMNA (0.53) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| Hydrochloric Acid SCHEMBL27655723 | 0.69 | LMNA (0.53) | LMNAL3MBTL1ALDH1A1FAAHPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57059858-A | — | — | None | — | — | JP | disclosed |
| JP-S5759858-A | SUBSTITUTED THIOBIURET DERIVATIVE | TAIHO YAKUHIN KOGYO KK | 1982-04-10 | — | — | JP | disclosed |