Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | PHGDH | O43175 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694830 | 0.81 | LMNA (1.00) | LMNAL3MBTL1FAAHPHGDHMGLL | |
| SCHEMBL1642674 | 0.79 | LMNA (0.68) | LMNAL3MBTL1FAAHPHGDHMGLL | |
| SCHEMBL10394940 | 0.78 | LMNA (0.66) | LMNAL3MBTL1FAAHPHGDHMGLL | |
| SCHEMBL27620586 | 0.77 | L3MBTL1 (0.44) | LMNAL3MBTL1FAAHPHGDHMGLL | |
| SCHEMBL5255044 | 0.75 | PKM (0.53) | LMNAL3MBTL1FAAHPHGDHMGLL | |
| SCHEMBL25137386 | 0.75 | FAAH (0.64) | LMNAL3MBTL1FAAHPHGDHMGLL | |
| SCHEMBL8848450 | 0.75 | FAAH (0.64) | LMNAL3MBTL1FAAHPHGDHMGLL | |
| SCHEMBL5433772 | 0.75 | L3MBTL1 (0.63) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL5961342 | 0.73 | FAAH (0.61) | LMNAL3MBTL1FAAHPHGDHMGLL | |
| SCHEMBL25137411 | 0.72 | LMNA (0.59) | LMNAL3MBTL1FAAHPHGDHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091524-A2 | COMBINATION THERAPY FOR TREATING HEPATITIS C INFECTIONS | Achillion Pharmaceuticals, Inc. (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2008076443-A2 | COMBINATION THERAPY FOR TREATING HEPATITIS C INFECTIONS | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-06-26 | — | — | WO | claimed |