Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215869 | 0.77 | NOTUM (0.46) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL11216758 | 0.72 | ABCB1 (0.39) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL11457185 | 0.72 | CA2 (0.40) | LMNAKDM4ECA12 | |
| SCHEMBL10861134 | 0.66 | DAO (0.38) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL11221894 | 0.64 | ABCC9 (0.41) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL2223445 | 0.63 | RARB (0.53) | PGRNSD2 | |
| SCHEMBL16905203 | 0.63 | PGR (0.42) | ABCB1PGRNSD2 | |
| SCHEMBL1391209 | 0.62 | NOTUM (0.46) | — | |
| SCHEMBL26892628 | 0.61 | KDM1A (0.57) | NSD2 | |
| SCHEMBL11213679 | 0.61 | ABCB1 (0.41) | ABCB1ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333759-A | Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones | FISONS LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |