Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700167 | 0.85 | MCL1 (0.50) | MCL1ALDH1A1GAACYP3A4KDM4E | |
| SCHEMBL16264605 | 0.81 | MCL1 (0.41) | MCL1ALDH1A1GAACYP3A4KDM4E | |
| SCHEMBL11205712 | 0.78 | MCL1 (0.54) | MCL1ALDH1A1GAACYP3A4KDM4E | |
| SCHEMBL2912153 | 0.77 | ACHE (0.48) | ALDH1A1KDM4EGLAACHESMN1; SMN2 | |
| SCHEMBL926842 | 0.74 | — | — | |
| SCHEMBL16379743 | 0.73 | ALDH1A1 (0.44) | MCL1ALDH1A1GAACYP3A4ACHE | |
| SCHEMBL13280958 | 0.73 | ALDH1A1 (0.44) | MCL1ALDH1A1GAACYP3A4ACHE | |
| SCHEMBL13301596 | 0.73 | ALDH1A1 (0.44) | MCL1ALDH1A1GAACYP3A4ACHE | |
| SCHEMBL10953891 | 0.72 | — | — | |
| SCHEMBL16264489 | 0.72 | MCL1 (0.47) | MCL1ALDH1A1GAACYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029719-B1 | VULCANIZABLE RUBBER COMPOSITIONS INHIBITED FROM PREMATURE VULCANIZATION BY METHYLENE THIOETHERS, AND NOVEL METHYLENE THIOETHERS | MONSANTO COMPANY (US) | 1983-02-16 | — | — | EP | disclosed |
| US-4342705-A | CONTAINING CARBONYL OR CYANO FUNCTIONAL GROUPS, USEFUL AS VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0029719-A1 | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers, and novel methylene thioethers | MONSANTO COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4271050-A | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers | MONSANTO COMPANY (US) | 1981-06-02 | — | — | US | disclosed |