Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214549 | 0.85 | MCL1 (0.48) | MCL1ALDH1A1L3MBTL1HSD17B10KDM4E | |
| SCHEMBL18120666 | 0.83 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1HSD17B10TP53KDM4E | |
| SCHEMBL28800571 | 0.82 | MCL1 (0.48) | MCL1ALDH1A1L3MBTL1HSD17B10KDM4E | |
| SCHEMBL11205712 | 0.81 | MCL1 (0.54) | MCL1ALDH1A1L3MBTL1HSD17B10KDM4E | |
| SCHEMBL11380647 | 0.81 | MCL1 (0.47) | MCL1ALDH1A1L3MBTL1HSD17B10KDM4E | |
| SCHEMBL1413000 | 0.78 | GAA (0.48) | ALDH1A1L3MBTL1HSD17B10KDM4ELMNA | |
| SCHEMBL16264605 | 0.77 | MCL1 (0.41) | MCL1ALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL9865139 | 0.76 | GAA (0.46) | ALDH1A1L3MBTL1HSD17B10KDM4ELMNA | |
| SCHEMBL17773075 | 0.76 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1HSD17B10TP53KDM4E | |
| SCHEMBL7713280 | 0.75 | GAA (0.55) | ALDH1A1L3MBTL1HSD17B10KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138971-A1 | PROCESS FOR SYNTHESIS OF RES METIROM AND ITS INTERMEDIATES THEREOF | ROYAL PHARMA (IN) | 2026-05-21 | — | — | US | claimed |
| EP-4691557-A2 | METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF | Madrigal Pharmaceuticals, Inc. (US) | 2026-02-11 | — | — | EP | claimed |
| US-20250115559-A1 | PREPARATION METHOD OF PYRIDAZINONE DERIVATIVE, AND INTERMEDIATE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2025-04-10 | — | — | US | claimed |
| EP-4477649-A1 | PREPARATION METHOD OF PYRIDAZINONE DERIVATIVE, AND INTERMEDIATE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-12-18 | — | — | EP | claimed |
| EP-4023641-B1 | METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF | MADRIGAL PHARMACEUTICALS INC (US) | 2024-05-01 | — | — | EP | claimed |
| WO-2024084491-A1 | PROCESS FOR SYNTHESIS OF RES METIROM AND ITS INTERMEDIATES THEREOF | MEHTA NILESH VIPINCHANDRA (IN) | 2024-04-25 | — | — | WO | claimed |
| WO-2023147779-A1 | PREPARATION METHOD OF PYRIDAZINONE DERIVATIVE, AND INTERMEDIATE THEREOF | 四川海思科制药有限公司 | 2023-08-10 | — | — | WO | claimed |
| EP-4023641-A2 | METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF | Madrigal Pharmaceuticals, Inc. (US) | 2022-07-06 | — | — | EP | claimed |
| US-20260138971-A1 | PROCESS FOR SYNTHESIS OF RES METIROM AND ITS INTERMEDIATES THEREOF | ROYAL PHARMA (IN) | 2026-05-21 | — | — | US | disclosed |
| CN-122036699-A | THR-beta modulators and methods of use thereof | 阿利戈斯治疗公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-122010848-A | Preparation method and detection method of key intermediate of dihydropyrido [4,3-d ] pyrimidinone analogue | 河北安健成益医药科技有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12617769-B2 | Chemical compound as thyroid hormone beta receptor agonist and use thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2026-05-05 | — | — | US | disclosed |
| CN-121824430-A | Preparation method of Resmetirom key intermediate | 江苏慧聚药业股份有限公司 | 2026-04-10 | — | — | CN | disclosed |
| US-12590072-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| EP-0029719-A1 | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers, and novel methylene thioethers | MONSANTO COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4271050-A | Vulcanizable rubber compositions inhibited from premature vulcanization by methylene thioethers | MONSANTO COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4266056-A | FUNGICIDES, BACTERICIDES | ZOECON CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| EP-0008277-A1 | Benzopyrano derivatives, pharmaceutical compositions containing them and processes for preparing the compounds and compositions | Technobiotic Ltd. (CH) | 1980-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260138971-A1 | PROCESS FOR SYNTHESIS OF RES METIROM AND ITS INTERMEDIATES THEREOF | CARM1, DAO, CA2 | MCL1 4130/4885ALDH1A1 63/4885L3MBTL1 2578/4885 |
| US-20250115559-A1 | PREPARATION METHOD OF PYRIDAZINONE DERIVATIVE, AND INTERMEDIATE THEREOF | PIR, PDXK, PNPO | MCL1 4135/4885ALDH1A1 1312/4885L3MBTL1 3773/4885 |
| US-12590072-B2 | Thyromimetics | THRB, TSHR, TRHR | MCL1 2500/4885ALDH1A1 2389/4885L3MBTL1 2286/4885 |
| US-12617769-B2 | Chemical compound as thyroid hormone beta receptor agonist and use thereof | THRB, TSHR, THRA | MCL1 3733/4885ALDH1A1 1340/4885L3MBTL1 2825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.