Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203434 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL6744642 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1POLBL3MBTL1GAA | |
| SCHEMBL11214768 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1POLBL3MBTL1GAA | |
| SCHEMBL9503715 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1POLBL3MBTL1GAA | |
| SCHEMBL1327130 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1POLBL3MBTL1GAA | |
| SCHEMBL29620411 | 0.77 | L3MBTL1 (0.58) | SMN1; SMN2ALDH1A1POLBL3MBTL1GAA | |
| SCHEMBL31150659 | 0.75 | NPC1 (0.60) | SMN1; SMN2ALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL5664569 | 0.75 | CA12 (0.50) | SMN1; SMN2ALDH1A1LMNAMAPTCA12 | |
| SCHEMBL2087969 | 0.74 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1POLBL3MBTL1GAA | |
| SCHEMBL2087971 | 0.74 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1POLBL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |