Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330537 | 0.86 | SRC (0.55) | SMN1; SMN2PLAUPOLBALDH1A1KDM4E | |
| SCHEMBL5520675 | 0.85 | SMN1; SMN2 (0.72) | SMN1; SMN2POLBKDM4EHTTHSD17B10 | |
| SCHEMBL6744642 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2POLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11214765 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBALDH1A1MAPK1HTT | |
| SCHEMBL9503715 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBALDH1A1MAPK1HTT | |
| SCHEMBL2291036 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2POLBALDH1A1KDM4EMAPK1 | |
| SCHEMBL1327130 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2POLBALDH1A1MAPK1TSHR | |
| SCHEMBL29620411 | 0.77 | L3MBTL1 (0.58) | SMN1; SMN2POLBALDH1A1MAPK1HTT | |
| SCHEMBL15953960 | 0.77 | MAPT (0.61) | SMN1; SMN2ALDH1A1TSHRGAAMAPT | |
| SCHEMBL31357493 | 0.77 | MAPT (0.61) | SMN1; SMN2ALDH1A1TSHRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |