Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209410 | 0.79 | CASP6 (0.60) | CASP6GAAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4649672 | 0.78 | CASP6 (0.50) | CASP6LMNAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL30726816 | 0.78 | CASP6 (0.50) | CASP6LMNAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7112143 | 0.78 | ABCC9 (0.51) | LMNAALDH1A1TDP1RORCHSD17B10 | |
| SCHEMBL30704480 | 0.78 | ABCC9 (0.51) | LMNAALDH1A1TDP1RORCHSD17B10 | |
| SCHEMBL12720517 | 0.77 | CASP6 (0.46) | CASP6LMNAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11407377 | 0.75 | CASP6 (0.51) | CASP6GAAALDH1A1TDP1MAPT | |
| SCHEMBL5081980 | 0.74 | CASP6 (0.58) | CASP6ALDH1A1TDP1CYP2C9CYP1A2 | |
| SCHEMBL7112439 | 0.73 | KCNJ11 (0.71) | CASP6 | |
| SCHEMBL10942538 | 0.71 | ALDH1A1 (0.48) | CASP6LMNAALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036143-B1 | PROCESS FOR THE PRODUCTION OF 1-AMINO-2-ETHOXY-NAPHTHALENE-6-SULPHONIC ACID | BAYER AG (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4341719-A | Process for the preparation of 1-amino-2-ethoxy-naphthalene-6-sulphonic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1982-07-27 | — | — | US | disclosed |
| EP-0036143-A1 | Process for the production of 1-amino-2-ethoxy-naphthalene-6-sulphonic acid | BAYER AG (DE) | 1981-09-23 | — | — | EP | disclosed |