Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.43 |
| ▸ | CD40 | P25942 | 1/20 | 0.42 |
| ▸ | CD40LG | P29965 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209410 | 0.83 | CASP6 (0.60) | CASP6ALDH1A1HIF1APRMT1CYP1A2 | |
| SCHEMBL8367846 | 0.78 | CASP6 (0.68) | CASP6ALDH1A1PRMT1CA2CA3 | |
| SCHEMBL4280353 | 0.78 | ALDH1A1 (0.54) | CASP6ALDH1A1HIF1APRMT1CYP1A2 | |
| SCHEMBL3203561 | 0.78 | ALDH1A1 (0.54) | CASP6ALDH1A1HIF1APRMT1CYP1A2 | |
| SCHEMBL4280346 | 0.76 | ALDH1A1 (0.53) | CASP6ALDH1A1HIF1APRMT1CYP1A2 | |
| SCHEMBL11759576 | 0.76 | ALDH1A1 (0.53) | CASP6ALDH1A1HIF1APRMT1CYP1A2 | |
| SCHEMBL20299286 | 0.76 | CASP6 (0.74) | CASP6ALDH1A1PRMT1CA2CA3 | |
| SCHEMBL9350146 | 0.75 | ALDH1A1 (0.52) | CASP6ALDH1A1HIF1APRMT1CYP1A2 | |
| SCHEMBL11215283 | 0.74 | CASP6 (0.53) | CASP6ALDH1A1PRMT1CYP1A2TDP1 | |
| SCHEMBL7112439 | 0.74 | KCNJ11 (0.71) | CASP6KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335411-B2 | Method of producing a tire composition having improved silica reinforcement | BRIDGESTONE CORPORATION (JP) | 2008-02-26 | — | — | US | disclosed |
| US-20060089446-A1 | Method of producing a tire composition having improved silica reinforcement | BRIDGESTONE CORPORATION | 2006-04-27 | — | — | US | disclosed |