SCHEMBL11215465

SCHEMBL11215465

O=S(=O)(Cl)c1cccc2cccc(Nc3ccccc3)c12

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.72
TTR P02766 1/20 0.72
CCNA2 P20248 1/20 0.72
CDK2 P24941 1/20 0.72
MAPK14 Q16539 1/20 0.72
NR4A1 P22736 1/20 0.70
FABP1 P07148 1/20 0.55
SNCA P37840 2/20 0.51
CHAT P28329 1/20 0.51
ALDH1A1 P00352 4/20 0.47
ATM Q13315 2/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
CDC25B P30305 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MAPT P10636 6/20 0.43
MEN1 O00255 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381891 0.84 FABP4 (1.00) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL43158 0.84 FABP4 (1.00) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL5680858 0.83 FABP4 (0.51) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL10353163 0.83 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL592279 0.83 NR4A1 (1.00) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL6654762 0.83 CDK2 (0.70) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL592280 0.83 NR4A1 (1.00) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL1786498 0.83 CDK2 (0.70) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL6654772 0.83 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL1786500 0.83 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4372745-A QUALITATIVE AND QUANTITATIVE ANALYSIS ELECTRO-NUCLEONICS, INC. (US) 1983-02-08 US disclosed