Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | CHAT | P28329 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215465 | 0.83 | FABP4 (0.72) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL20766620 | 0.80 | CA2 (0.62) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL28032037 | 0.80 | ALK (0.57) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL6264332 | 0.80 | FABP4 (0.70) | FABP4TTRCCNA2CDK2MAPK14 | |
| Ammonia Solution, Strong SCHEMBL1556275 | 0.78 | NR4A1 (0.71) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL14632174 | 0.76 | FABP4 (0.47) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL14215794 | 0.76 | FABP4 (0.47) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL4748579 | 0.74 | CA1 (0.45) | ALDH1A1TDP1HSD17B10 | |
| SCHEMBL27345005 | 0.73 | FABP4 (0.49) | FABP4TTRCCNA2CDK2MAPK14 | |
| SCHEMBL444976 | 0.72 | MAPT (0.70) | FABP4SNCAALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932600-B1 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1BETA CONVERTING ENZYME INHIBITORS | WARNER LAMBERT CO (US) | 2006-02-08 | — | — | EP | disclosed |