Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15665083 | 0.87 | MAPT (0.42) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL27974603 | 0.68 | ALDH1A1 (0.38) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL18485267 | 0.68 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL14805661 | 0.67 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL3453639 | 0.65 | EPAS1 (0.42) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL11600529 | 0.64 | MAPT (0.54) | MAPTKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL3453468 | 0.63 | EPAS1 (0.41) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL6691525 | 0.61 | MAPT (0.55) | MAPTKDM4EALDH1A1HSD17B10TP53 | |
| SCHEMBL18193688 | 0.61 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10KMT2A | |
| Thiram SCHEMBL9732905 | 0.61 | ALDH1A1 (0.59) | MAPTKDM4EALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4383071-A | CUSHIONING; INSULATION; COATINGS; COLD RESISTANCE; FLEXIBILITY | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1983-05-10 | — | — | US | disclosed |