Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiram SCHEMBL11215468 | 0.87 | MAPT (0.33) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL18485267 | 0.78 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL14805661 | 0.77 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL11600529 | 0.74 | MAPT (0.54) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL3453639 | 0.72 | EPAS1 (0.42) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL6691525 | 0.71 | MAPT (0.55) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL18193688 | 0.70 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL3453468 | 0.70 | EPAS1 (0.41) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL1880698 | 0.69 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL30856492 | 0.69 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1HSD17B10EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3730547-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2020-10-28 | — | — | EP | disclosed |
| US-9650502-B2 | Process for the preparation of nitrile rubbers | VERSALIS S.P.A. (IT) | 2017-05-16 | — | — | US | disclosed |
| EP-2723776-B1 | PROCESS FOR THE PREPARATION OF NITRILE RUBBERS | VERSALIS SPA (IT) | 2015-04-08 | — | — | EP | disclosed |
| US-20140124986-A1 | PROCESS FOR THE PREPARATION OF NITRILE RUBBERS | VERSALIS S.P.A. (IT) | 2014-05-08 | — | — | US | disclosed |