Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 9/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222783 | 0.86 | PNP (0.36) | PNPPDE2AADORA2AADORA2BPDE1A | |
| SCHEMBL11215534 | 0.82 | PNP (0.53) | PNPPDE2AADORA2AADORA2BADORA1 | |
| SCHEMBL7617790 | 0.81 | PNP (0.36) | PNPHPRT1PDE2AADORA2AADORA2B | |
| SCHEMBL17580687 | 0.77 | MEN1 (0.44) | PNPHPRT1 | |
| SCHEMBL6035387 | 0.76 | ADORA2A (0.42) | PNPADORA2AADORA2BADORA1 | |
| SCHEMBL7617801 | 0.76 | ADORA2A (0.40) | PNPPDE2AADORA2AADORA2BPDE1A | |
| SCHEMBL7050396 | 0.74 | PNP (0.36) | PNP | |
| SCHEMBL5667528 | 0.74 | ADORA2B (0.47) | PNPADORA2AADORA2BADORA1 | |
| SCHEMBL7055773 | 0.72 | PNP (0.35) | PNPADORA2AADORA2B | |
| SCHEMBL27547350 | 0.72 | TK1 (0.32) | PNPHPRT1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1982002202-A1 | NOVEL DERIVATIVES OF GUANINE | ASTRA LAEKEMEDEL AB (SE) | 1982-07-08 | — | — | WO | disclosed |