Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA3 | P07451 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA6 | P23280 | 4/20 | 0.38 |
| ▸ | CA5A | P35218 | 4/20 | 0.38 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098356 | 0.99 | CISD1 (0.43) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11104031 | 0.87 | CA12 (0.48) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11097101 | 0.84 | CISD1 (0.44) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11100547 | 0.84 | CISD1 (0.44) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11096601 | 0.84 | ALDH1A1 (0.43) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11101859 | 0.84 | ALDH1A1 (0.43) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11101179 | 0.83 | CISD1 (0.45) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11104381 | 0.83 | ALDH1A1 (0.43) | CISD1CA12CA1CA2CA3 | |
| SCHEMBL11555157 | 0.80 | CISD1 (0.48) | CISD1CA1CA2CA4CA9 | |
| SCHEMBL11223169 | 0.76 | CISD1 (0.46) | CISD1CA1CA2PDE4DPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339446-A | 5-Sulfamoyl-orthanilic acids, processes for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-13 | — | — | US | disclosed |