SCHEMBL11216688

SCHEMBL11216688

CC(C(=O)O)[N+]([O-])=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 4/20 0.43
TDP1 Q9NUW8 4/20 0.41
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
HTT P42858 1/20 0.39
AKR1C3 P42330 1/20 0.38
GLA P06280 1/20 0.38
G6PD P11413 2/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
PRMT1 Q99873 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11216687 1.00 FBP1 (0.43) FBP1TDP1ALDH1A1KMT2ANPC1
SCHEMBL11216686 1.00 FBP1 (0.43) FBP1TDP1ALDH1A1KMT2ANPC1
SCHEMBL7226576 0.81 ALDH1A1 (0.46) FBP1TDP1ALDH1A1KMT2ANPC1
SCHEMBL7226574 0.81 ALDH1A1 (0.46) FBP1TDP1ALDH1A1KMT2ANPC1
SCHEMBL13924679 0.79 NPC1 (0.45) FBP1TDP1ALDH1A1NPC1RAB9A
SCHEMBL566832 0.79 NPC1 (0.45) FBP1TDP1ALDH1A1NPC1RAB9A
SCHEMBL8700570 0.78 NPC1 (0.46) FBP1TDP1ALDH1A1KMT2ANPC1
SCHEMBL7227355 0.77 TDP1 (0.45) FBP1TDP1ALDH1A1KMT2ANPC1
SCHEMBL8696711 0.75 TSHR (0.49) TDP1ALDH1A1KMT2ANPC1RAB9A
SCHEMBL4022056 0.73 NPC1 (0.51) FBP1TDP1ALDH1A1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4399149-A Fungicides SHELL OIL COMPANY (US) 1983-08-16 US disclosed
EP-0057027-A2 Fungicides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1982-08-04 EP disclosed