Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226574 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL11216687 | 0.81 | FBP1 (0.43) | ALDH1A1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL11216686 | 0.81 | FBP1 (0.43) | ALDH1A1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL11216688 | 0.81 | FBP1 (0.43) | ALDH1A1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL7227355 | 0.73 | TDP1 (0.45) | ALDH1A1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL7227347 | 0.72 | KMT2A (0.47) | ALDH1A1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL7227352 | 0.72 | KMT2A (0.47) | ALDH1A1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL8667692 | 0.70 | MAPT (0.40) | ALDH1A1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL4091240 | 0.70 | MAPT (0.40) | ALDH1A1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL4091245 | 0.70 | MAPT (0.40) | ALDH1A1KMT2ATDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660734-B1 | Oxazinones having antibacterial activity | SIMON FRASER UNIVERSITY (CA) | 2003-12-09 | — | — | US | disclosed |
| WO-2003020709-A1 | 1,2-OXAZIN-3-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS | SIMON FRASER UNIVERSITY (CA) | 2003-03-13 | — | — | WO | disclosed |
| US-6399600-B1 | ANTIBIOTIC RESISTANT BATERIA INFECTIONS | SIMON FRASER UNIVERSITY (CA) | 2002-06-04 | — | — | US | disclosed |