Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216687 | 0.77 | FBP1 (0.43) | TDP1ALDH1A1KMT2AFBP1NPC1 | |
| SCHEMBL11216686 | 0.77 | FBP1 (0.43) | TDP1ALDH1A1KMT2AFBP1NPC1 | |
| SCHEMBL11216688 | 0.77 | FBP1 (0.43) | TDP1ALDH1A1KMT2AFBP1NPC1 | |
| SCHEMBL7226574 | 0.73 | ALDH1A1 (0.46) | TDP1ALDH1A1KMT2AFBP1NPC1 | |
| SCHEMBL7226576 | 0.73 | ALDH1A1 (0.46) | TDP1ALDH1A1KMT2AFBP1NPC1 | |
| SCHEMBL13924679 | 0.71 | NPC1 (0.45) | TDP1ALDH1A1FBP1NPC1RAB9A | |
| SCHEMBL566832 | 0.71 | NPC1 (0.45) | TDP1ALDH1A1FBP1NPC1RAB9A | |
| SCHEMBL8700570 | 0.70 | NPC1 (0.46) | TDP1ALDH1A1KMT2AFBP1NPC1 | |
| SCHEMBL7226580 | 0.69 | TDP1 (0.53) | TDP1ALDH1A1KMT2AFBP1CYP2C19 | |
| SCHEMBL7226581 | 0.69 | TDP1 (0.53) | TDP1ALDH1A1KMT2AFBP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660734-B1 | Oxazinones having antibacterial activity | SIMON FRASER UNIVERSITY (CA) | 2003-12-09 | — | — | US | disclosed |
| WO-2003020709-A1 | 1,2-OXAZIN-3-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS | SIMON FRASER UNIVERSITY (CA) | 2003-03-13 | — | — | WO | disclosed |
| US-6399600-B1 | ANTIBIOTIC RESISTANT BATERIA INFECTIONS | SIMON FRASER UNIVERSITY (CA) | 2002-06-04 | — | — | US | disclosed |