Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222310 | 1.00 | FBP1 (0.62) | FBP1MAPTMAOBLMNAGLO1 | |
| SCHEMBL11216772 | 0.90 | MAPT (0.62) | FBP1MAPTMAOBLMNAGLO1 | |
| SCHEMBL7828363 | 0.90 | MAPT (0.62) | FBP1MAPTMAOBLMNAGLO1 | |
| SCHEMBL7828360 | 0.90 | MAPT (0.62) | FBP1MAPTMAOBLMNAGLO1 | |
| SCHEMBL11218837 | 0.85 | BCHE (0.56) | FBP1MAPTMAOBALDH1A1TSHR | |
| SCHEMBL11218840 | 0.85 | BCHE (0.56) | FBP1MAPTMAOBALDH1A1TSHR | |
| SCHEMBL28236366 | 0.82 | NFE2L2 (0.63) | FBP1MAPTMAOBLMNAGLO1 | |
| SCHEMBL11441716 | 0.81 | FBP1 (0.78) | FBP1MAPTMAOBLMNAGLO1 | |
| SCHEMBL27945148 | 0.81 | FBP1 (0.68) | FBP1MAPTMAOBLMNAGLO1 | |
| SCHEMBL8866005 | 0.79 | GLO1 (0.64) | FBP1MAPTMAOBLMNAGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342781-A | PREVENTING AND TREATING ALLERGIC BRONCHIAL ASTHMA, RHINITIS AND SKIN DISORDERS | PFIZER INC. (US) | 1982-08-03 | — | — | US | disclosed |